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| Part No. | GB01009 | |||
| CAS NO: | 2682-20-4 | |||
| Ingredients | Isothiazolinone Activity | |||
| Content of active ingredients | 9.5~9.9% (w/w) | |||
| Molecular Formula | C4H5NOS (MIT) | |||
| Molecular Weight : | 115.1 | |||
| Applicable PH range | 2~12 | |||
| Brand: | Neocide® | |||
| Usage: | ||||
| NeoCide PC-950 is 9.5% methyl isothiazolinone aqueous solution (containing synergistic agent phenoxyethanol/ octanediol), miscible with water. Recommended use level is 0.05 by weight (~50ppm) in IVD buffers, diluent, and detergents, and 0.075% (~75 ppm) for clinical chemistry and immunoassay, enzyme, antibody, IA/EIA. Typically 0.1% (~100ppm) for calibrator/controls with a high concentration of serum. NeoCide PC-950 can be a replacement of Sodium Azide and application pH from 2-12. | ||||
Description:
NeoCide PC-950 preservative is a highly effective biocide for controlling microorganisms in biological media for in vitro diagnostic (IVD) products. Suitable media include reagents, control solutions, calibration solutions, buffers, ISE, GIA (Colloidal Gold Immunoassay), EIA (Enzyme Immunoassay),blood cell, blood type test reagent and mobile phases. With broad-spectrum activity, excellent compatibility and stability, and low toxicity and biodegradable at use levels.NeoCide PC-950 preservative is the ideal choice for replacing Thimerosal, Sodium Azide, and Gentamicin. NeoCide PC-950 preservative eradicates bacteria, fungi, and yeasts in reagents for prolonged periods, thereby increasing a product's shelf life and open vial stability. The water solubility permits easy incorporation into IVD reagents. NeoCide PC-950 preservative does not affect the functionality of most enzyme- or antibody-linked reactions, and will not interfere with assay indicators.
Key Advantage:
Due to its broad-spectrum activity, excellent compatibility and stability, as well as low toxicity at working concentrations, it has become an ideal and efficient antibacterial agent in in vitro diagnostic reagents, replacing stacking
The best product of sodium nitrate, with a particularly wide pH range, can be used in all reagent formulations with pH 2-12.
broad-spectrum antibacterial ability, effective against bacteria (including both Gram-positive and Gram-negative), fungi, and yeast.
formulated with a wide range of ingredients such as anionic, cationic, and nonionic surfactants.
Excellent chemical stability, good compatibility with most raw materials or formulations, and free from metal ions.
The solvent used does not interfere with the reagent reaction system and is compatible with key enzymes.
Does not affect antibody binding, no interference with ion-selective electrodes (ISE).
The applicable acid-base range is wider (pH 2~12), and it can also inhibit bacteria at pH ≤ 3.5 or >10.5.
Better temperature stability, more stable at high temperatures, and the stability of unopened products can last for more than three years.
Completely soluble in water, suitable for water-based solution formulations, and exhibits good stability in reagent kits (pH 2~12).
Chemical Composition
The active ingredient of Niu Sha PC-950 antibacterial agent is 9.5% methylisothiazolinone (2-Methyl-4-isothiazolin-3-one, MIT) water Solution. The active ingredient comes from an internationally renowned chemical company.
Application
Neocide@ PC-950 antimicrobial agent is specifically designed for in vitro diagnostic reagents (IVD). It includes biochemical reagents, immune reagents, molecular biology reagents, etc
Reagents, quality control materials, calibration standards, ion-selective electrodes (ISE), colloidal gold method (GIA), enzyme immunoassay (EIA), blood cell preservation, blood
Type inspection reagents, mobile phases in chromatography, electrophoresis solutions, PCR/DNA testing related reagents, various diluents, buffers, cleaning solutions, etc.
The special advantage is that it can be used in high pH solutions, solutions containing human serum, solutions containing BSA, and solutions containing TWEEN. Due to
Due to its wide adaptability to pH values, the application range of Nusha PC-950 bacteriostatic agent is greater than that of other bacteriostatic agents. Warning: This product must not be used as food.
Use of beverage additives or preservatives.
The recommended concentration is 0.05% to 0.1% (active ingredient MIT approximately).
50~100PPM). At this concentration, the product is safe and does not
May cause mutations, birth defects, cancer, or affect the reproductive system in humans.
Generally, the Nusha PC-950 antibacterial agent is used for in vitro diagnostic reagents
The last ingredient added, it is recommended to add it when the solution temperature is lower than
45oC, although the product itself can withstand temperatures as high as 70oC
But it is not recommended to use at this temperature
