PC-300 preservative is a widely used bacteriostatic agent for in vitro diagnostic reagents. Its main active ingredients are a mixture of two isothiazolinones: 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-Methyl-4-isothiazolin-3-one (MIT), with a content ratio of 3:1, and the total concentrati

Liquid biopsies, based on cell free DNA (cfDNA) and proteins, have shown the potential to detect early stage cancers of diverse tissue types. However, most of these studies were retrospective, using individuals previously diagnosed with cancer as cases and healthy individuals as controls. Here, we d